Rhodiola Rosea + Saffron 60Vcaps Nutripure
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- stress - anxiety - cortisol - stress-related cravings
- memory & cognitive function
- endurance - strength - muscle growth - recovery
- sexual function...
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Product Description
Composition
Rhodiola rosea, also known as roseroot, is a perennial plant that grows in mountainous regions of the northern hemisphere in Asia, Europe, and North America.
It has been known since ancient times for its many therapeutic properties and is considered an adaptogenic plant, which means that it helps the body adapt to different types of stress.
The active principles of the plant are mainly concentrated in its roots, which contain organic acids, flavonoids, tannins and phenolic glycosides. The main compounds necessary for therapeutic activity are rhodioloside, tyrosol, rosavine, rosarine, rosin and rhodioline.
Organic acids found in the plant, such as caffeic acid and chlorogenic acid, have antioxidant properties. Numerous studies have been carried out on Rhodiola rosea, mainly in Russia, the United States, Switzerland, Norway, Finland, Japan and China, and have confirmed its effectiveness as a relaxant, nootropic and antioxidant.
Saffron is a spice that has been cultivated for millennia and originates from the regions of Persia, which today correspond to Iran. It is obtained from the cultivation of the plant Crocus sativus L. and is recognized mainly thanks to its yellow-orange color, due to its phytochemicals.
Over the centuries, it has been attributed many virtues, but the best known is certainly its antidepressant effect associated with safranal, an organic compound isolated from this spice.
Saffron is also rich in crocin, a carotenoid that gives it antioxidant and antidepressant properties, and picrocrocin, responsible for its bitter taste. When combined with Rhodiola, another herbal remedy, it can reduce anxiety, fatigue, and mood disorders such as depression.
A study in 45 adults with mild to moderate depression showed that the fixed combination of rhodiola and saffron had significant effects in improving depression and anxiety after 6 weeks of supplementation.
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(3) Nathalie Mougin. 2011. Roseroot (Rhodiola Rosea): From its traditional use to a therapeutic future. Pharmaceutical sciences.
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(10) FASTIER A. 1996. Isolation and identification of flavonoids from Strogylodon lucidus. Veterinary thesis. Lyons. 126 pages
(11) Mounnissamy, V. M & Kavimani, S. & Gunasegaran, R. 2002. Antibacterial activity of gossypetin isolated from Hibiscus sabdariffa. Antiseptic. 81-82.
(12) Khan, Amitava et al. 2013. Gossypetin, a naturally occurring hexahydroxy flavone, ameliorates gamma radiation-mediated DNA damage. International journal of radiation biology.
(13) Philippe Bouchet. 2021. TANNINS or TANNINS. Encyclopaedia Universalis.
(14) Cusumano C. 2005. Determination of procyanidins in various alpine plants. Zion HEVs. 572-591.
(15) Xavier Leverve. 2008. Catechins and health, state of knowledge. INRA.
(16) Santos-Bulga C. P , Scalbert A. 2000. Proanthocyanidins and tannins like natural compound. Dietary intake and effects on nutrition and health. 1094-1117.
(17) Kelly G. S 2001. Rhodiola rosea: a possible plant adaptogen. Alternative Medicine Review. 293-302.
(18) Shi, Ty. , Feng, Sf. , Xing, Jh. et al. 2012. Neuroprotective Effects of Salidroside and its Analogue Tyrosol Galactoside Against Focal Cerebral Ischemia In Vivo and H2O2-Induced Neurotoxicity In Vitro. Neurotox Res 21, 358–367.
(19) Clement Donnadieu. 2017. Rhodiola rosea and its interest as an adaptogenic plant in athletes.
(20) Directorate General for Competition, Consumer Affairs and Fraud Prevention. Food supplements - Plants. Ministry of Economy, Finance and Recovery.
(21) Summary of Product Characteristics Rodizen
(22) Darninvan V. , Kteyan A. , Panossian A. , Gabrielyan E. , Wikman G. , Wagner H. 2000. Rhodiola rosea in stress-induced fatigue. A double blind cross-over study of standardized extract SHR-5 with repeated low-dose regimen on the mental performance of healthy physicians during night-duty. Phytomedicine. 365-37.
(23) Spasov A. et al. 2000. A double blind, placebo controlled pilot of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine. 85-89.
(24) Panossian A, Wikman G, Sarris J. Rosenroot (Rhodiola rosea). 2010. Traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine 17. 481–493.
(25) Shevtsov V. AT , Zholbus B. I , Shervaly V. I , Volskij V. B , Korovin Y. P 2003. A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine. 95-105.
(26) De Bock et al. 2004. Acute Rhodiola rosea intake can improve endurance exercise performance.
(27) Maimeskulova L. AT , Maslov L. N, Lishmanov I. B, Krasnov E. AT 1997. The participation of the μ, δ and κ-opioid receptors in the realization of the antiarrhythmic effect of Rhodiola rosea. Eksp Klin Farmakol. 1997. 38-39.
(28) Zhang Z. et al. 1998. The effect of Rhodiola rosea capsules on oxygen consumption of myocardium and coronary artery blood flow in dogs. Zhongguo Zhong Yao Za Zhi. 104-106.
(29) Battistelli M. et al. 2005. Rhodiola rosea is an antioxidant in red blood cells: ultra structural and hemolytic behavior. European Journal Histochemistry. 243-254.
(30) Thomas, David Busti and Margarethe Maillart, December 2010. The uses and history of saffron. ENS biology Lyon.
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(32)YQ. Zheng, JX. Liu, JN. Wang, L. Xu. 2006. Effects of crocin on reperfusion-induced oxidative/nitrative injury to cerebral microvessels after global cerebral ischemia. Brain Res. 1138: 86-94.
(33) Akhondzadeh, Shahin et al. 2004. “Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816]. “BMC complementary and alternative medicine vol. 4 12.
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(35) Bangratz M, Ait Abdellah S, Berlin A, et al. Jul 2018. A preliminary assessment of a combination of rhodiola and saffron in the management of mild-moderate depression. Neuropsychiatr says Treat. 14:1821-1829.
(36) Green Plant Extracts. Saffron and stress, scientific file.
(37) Akhondzadeh S. , Harirchian M. , Shaffie-Sabet M. 2010. Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and placebo-controlled trial. Journal of Clinical Pharmacy and Therapeutics. 35 (5), p. 581-588.
(38) Esmail Moshiri, Afshin Akhondzadeh Basti, Ahamad-Ali Noorbala, Amir-Hossein Jamshidi, Seyed Hesameddin Abbasi, Shahin Akhondzadeh. 2006. Crocus sativus L. (petal) in the treatment of mild-to-moderate depression: A double-blind, randomized and placebo-controlled trial. Phytomedicine. Volume 13, Issues 9–10, 2006, Pages 607-611.
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(40) Nabavizadeh, Fatemeh & Salimi, Ehsan & Sadroleslami, Zahra & Karimian, Seyed & Vahedian-ardakani, Jalal. 2009. Saffron (Crocus sativus) increases gastric acid and pepsin secretions in rats: Role of nitric oxide (NO). African Journal of Pharmacy and Pharmacology. 3 181-184.
(41) Kianbakht, Mozafari. 2009. Effects of saffron and its active constituents, crocin and safranal, on prevention of indomethacin induced gastric ulcers in diabetic and nondiabetic rats. Journal of medicinal plants. pages 30-38.
(42) Bangratz M, Ait Abdellah S, Berlin A, et al. Jul 2018. A preliminary evaluation of a combination of rhodiola and saffron in the management of mild to moderate depression. Neuropsychiatrist DisTreat. 14:1821-1829.
Nutritional information
INSTRUCTIONS FOR USE
In the Russian tradition, it is recommended to take the plant for 3 weeks, then to stop 1 to 2 weeks before resuming the cycle.
TO BE PREFERRED
- Morning or midday at the start of a meal
Warnings
Warnings: Cannot replace a varied and balanced diet, and a lifestyle. Do not exceed the recommended daily dose. Keep out of the reach of young children. Store away from heat and humidity.
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