Rhodiola Rosea + Saffron 60Vcaps Nutripure

Discover Rhodiola Rosea, an adaptogenic plant traditionally used for centuries in Scandinavian countries, Russia and Asia where it grows on rocky slopes.

Thanks to its many benefits, Rhodiola has become an ally of choice for improving resistance and physical condition. It is ideal for athletes looking to improve their endurance and physical performance.

Rhodiola is also known for its antioxidant properties which protect the cells of our body.

But its benefits don't stop there. In fact, Rhodiola improves blood circulation, which has a positive effect on cerebral performance and the organism's reactivity.

Our Rhodiola Rosea is combined with saffron extract, which helps maintain emotional balance and a positive mood. The two ingredients combined provide optimal support for intellectual and cognitive activity.

Nutripure is committed to providing the highest quality Rhodiola Rosea and Saffron extracts, concentrated and standardized to ensure the presence of active ingredients. Each capsule contains 600mg of Rhodiola Rosea and 15mg of saffron, titrated in active ingredients for maximum effect.

The vegetarian capsule releases both ingredients into the body, for optimal support of your physical and mental health.

So don't wait any longer, try our Rhodiola Rosea to improve your resistance to stress and your physical condition, as well as to support optimal intellectual and cognitive activity. Choose quality and efficiency with our Rhodiola + Safran.

Rhodiola is a plant used for its properties on stress, sleep and cognitive functions, widely consumed in the form of food supplements which are regulated to guarantee their quality and safety. The standard extract used is SHR-5.

Rhodiola rosea extract is an adaptogen that stimulates non-specific resistance to different stressful situations. The following mechanisms of action are described: normalization of monoamine, cortisol and the transformation of β-endorphins, modulation of the body's primary stress reaction system, the HHS system, antioxidant effect and increase in ATP levels .

There are contraindications in pregnant women and in patients with bipolar disorder. Side effects such as over-excitement and restlessness may occur when taking Rhodiola. In this case, it is recommended to decrease the dosage and gradually increase it. It is also recommended not to take rhodiola in the evening so as not to disturb sleep.

Saffron has low toxicity when administered orally.

(1) Bouillard Bernard. 1997. Dictionary of plants and fungi. Editions Estem. 875 pages.

(2) Bremness L. 2002. Aromatic and medicinal plants. Editions Bordas. 303 pages.

(3) Nathalie Mougin. 2011. Roseroot (Rhodiola Rosea): From its traditional use to a therapeutic future. Pharmaceutical sciences.

(4) Brown R. P , Gerbarg P. I , Ramazanov Z. 2002. Rhodiola rosea: A phytomedicinal overview. Herbal Gram Journal. 40-52.

(5) Brekhman I. , Dardymov I. v. 1969. New substances of plant origin which increase nonspecific resistance. Annual Review of Pharmacology and Toxicology. 167-172

(6) Chapmann and Hall. 2008. The dictionary of natural substances. 1254 pages

(7) National Academy of Pharmacy. 2016. Chlorogenic (acid), pharmacognosy. University of Strasbourg.

(8) Marinova, Emma & Toneva, A. & Yanishlieva, N. 2009. Comparison of the antioxidative properties of caffeic and chlorogenic acids. Food Chemistry - FOOD CHEM. 114.

(9) Rohloff J. 2002. Volatile rhizomes of Rhodiola rosea. Phytochemistery. Volume 59. 655-661.

(10) FASTIER A. 1996. Isolation and identification of flavonoids from Strogylodon lucidus. Veterinary thesis. Lyons. 126 pages

(11) Mounnissamy, V. M & Kavimani, S. & Gunasegaran, R. 2002. Antibacterial activity of gossypetin isolated from Hibiscus sabdariffa. Antiseptic. 81-82.

(12) Khan, Amitava et al. 2013. Gossypetin, a naturally occurring hexahydroxy flavone, ameliorates gamma radiation-mediated DNA damage. International journal of radiation biology.

(13) Philippe Bouchet. 2021. TANNINS or TANNINS. Encyclopaedia Universalis.

(14) Cusumano C. 2005. Determination of procyanidins in various alpine plants. Zion HEVs. 572-591.

(15) Xavier Leverve. 2008. Catechins and health, state of knowledge. INRA.

(16) Santos-Bulga C. P , Scalbert A. 2000. Proanthocyanidins and tannins like natural compound. Dietary intake and effects on nutrition and health. 1094-1117.

(17) Kelly G. S 2001. Rhodiola rosea: a possible plant adaptogen. Alternative Medicine Review. 293-302.

(18) Shi, Ty. , Feng, Sf. , Xing, Jh. et al. 2012. Neuroprotective Effects of Salidroside and its Analogue Tyrosol Galactoside Against Focal Cerebral Ischemia In Vivo and H2O2-Induced Neurotoxicity In Vitro. Neurotox Res 21, 358–367.

(19) Clement Donnadieu. 2017. Rhodiola rosea and its interest as an adaptogenic plant in athletes.

(20) Directorate General for Competition, Consumer Affairs and Fraud Prevention. Food supplements - Plants. Ministry of Economy, Finance and Recovery.

(21) Summary of Product Characteristics Rodizen

(22) Darninvan V. , Kteyan A. , Panossian A. , Gabrielyan E. , Wikman G. , Wagner H. 2000. Rhodiola rosea in stress-induced fatigue. A double blind cross-over study of standardized extract SHR-5 with repeated low-dose regimen on the mental performance of healthy physicians during night-duty. Phytomedicine. 365-37.

(23) Spasov A. et al. 2000. A double blind, placebo controlled pilot of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine. 85-89.

(24) Panossian A, Wikman G, Sarris J. Rosenroot (Rhodiola rosea). 2010. Traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine 17. 481–493.

(25) Shevtsov V. AT , Zholbus B. I , Shervaly V. I , Volskij V. B , Korovin Y. P 2003. A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine. 95-105.

(26) De Bock et al. 2004. Acute Rhodiola rosea intake can improve endurance exercise performance.

(27) Maimeskulova L. AT , Maslov L. N, Lishmanov I. B, Krasnov E. AT 1997. The participation of the μ, δ and κ-opioid receptors in the realization of the antiarrhythmic effect of Rhodiola rosea. Eksp Klin Farmakol. 1997. 38-39.

(28) Zhang Z. et al. 1998. The effect of Rhodiola rosea capsules on oxygen consumption of myocardium and coronary artery blood flow in dogs. Zhongguo Zhong Yao Za Zhi. 104-106.

(29) Battistelli M. et al. 2005. Rhodiola rosea is an antioxidant in red blood cells: ultra structural and hemolytic behavior. European Journal Histochemistry. 243-254.

(30) Thomas, David Busti and Margarethe Maillart, December 2010. The uses and history of saffron. ENS biology Lyon.

(31) Ferrence S. VS , Bendersky G. 2004. Therapy with Saffron and the Goddess at Thera. Perspectives in Biology and Medicine, 47 n°2. 199-226

(32)YQ. Zheng, JX. Liu, JN. Wang, L. Xu. 2006. Effects of crocin on reperfusion-induced oxidative/nitrative injury to cerebral microvessels after global cerebral ischemia. Brain Res. 1138: 86-94.

(33) Akhondzadeh, Shahin et al. 2004. “Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816]. “BMC complementary and alternative medicine vol. 4 12.

(34) Schmidt M. et al. 2007. Saffron in phytotherapy: pharmacology and clinical uses. Wiener Medizinische Wochenschrift, 157 n°13-14. 315-319.

(35) Bangratz M, Ait Abdellah S, Berlin A, et al. Jul 2018. A preliminary assessment of a combination of rhodiola and saffron in the management of mild-moderate depression. Neuropsychiatr says Treat. 14:1821-1829.

(36) Green Plant Extracts. Saffron and stress, scientific file.

(37) Akhondzadeh S. , Harirchian M. , Shaffie-Sabet M. 2010. Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and placebo-controlled trial. Journal of Clinical Pharmacy and Therapeutics. 35 (5), p. 581-588.

(38) Esmail Moshiri, Afshin Akhondzadeh Basti, Ahamad-Ali Noorbala, Amir-Hossein Jamshidi, Seyed Hesameddin Abbasi, Shahin Akhondzadeh. 2006. Crocus sativus L. (petal) in the treatment of mild-to-moderate depression: A double-blind, randomized and placebo-controlled trial. Phytomedicine. Volume 13, Issues 9–10, 2006, Pages 607-611.

(39) Akhondzadeh S. , Kamalipour M. 2011. Cardiovascular Effects of Saffron: An Evidence-Based Review. The Journal of Tehran Heart Center. p.p. 59-61.

(40) Nabavizadeh, Fatemeh & Salimi, Ehsan & Sadroleslami, Zahra & Karimian, Seyed & Vahedian-ardakani, Jalal. 2009. Saffron (Crocus sativus) increases gastric acid and pepsin secretions in rats: Role of nitric oxide (NO). African Journal of Pharmacy and Pharmacology. 3 181-184.

(41) Kianbakht, Mozafari. 2009. Effects of saffron and its active constituents, crocin and safranal, on prevention of indomethacin induced gastric ulcers in diabetic and nondiabetic rats. Journal of medicinal plants. pages 30-38.

(42) Bangratz M, Ait Abdellah S, Berlin A, et al. Jul 2018. A preliminary evaluation of a combination of rhodiola and saffron in the management of mild to moderate depression. Neuropsychiatrist DisTreat. 14:1821-1829.