Bioactive Myo-Inositol – 60Vcaps Zein Pharma

Product description

Inositol is a substance similar to a vitamin, it was long called vitamin B8 and classified in the category of vitamin B complex. Following the discovery that the human body is actually able to produce Inositol itself from glucose, it is therefore no longer considered a vitamin, although it assumes of paramount importance within the organization.

Inositol influences the formation of the feel-good hormone serotonin, which plays an important role in depression and nervousness. Inositol is also important for the transmission of nerve impulses and neurotransmitters and influences metabolism hormones as well as sex hormones.

PCOS (polycystic ovary syndrome) is a metabolic disorder in which there is an increase in the production of certain hormones, including estosterone. At the same time, the metabolism of sugars and fats is also disturbed. This results in irregularities in the menstrual cycle, enlargement of the ovaries and poor quality eggs. Women with PCOS are at higher risk for several diseases and may experience infertility issues. For women who want to have children, this is not only a devastating diagnosis, but also an extremely stressful time.

Recent studies indicate that taking inositol in combination with folate (vitamin B9) regulates hormones and can therefore improve fertility. Inositol regulates the female cycle so that ovulation can occur regularly.

Inositol and fertility studies:

Review : 3600 infertile women with polycystic ovary syndrome should take 2000mg of myoinositol and 200 mcg of folic acid daily for 12 weeks. In 70% of women, the combined dose allowed a new ovulation. In addition, 545 pregnancies occurred, which corresponds to a pregnancy rate of 15%.

In the same study, in 19 pregnant women, an additional treatment with clomiphene or dexamethasone was carried out before pregnancy, in order to regulate the hormonal cycle and balance and to trigger the ovulation. Evaluation of blood values ​​showed that testosterone concentration could be lowered by treatment with myo-inositol and folic acid and progesterone concentration could be increased and therefore the values ​​approached the normal range: testosterone from about 97 ng/ml to about 43 ng/ml and progesterone from about 2 ng/ml to 12 ng/ml. No side effects have occurred as a result of taking these active ingredients.

Randomized, double-blind, placebo-controlled trial : 92 patients randomized, 47 received 400µg of folic acid as placebo, and 45 received more acidic myo-inositol (4g myo-inositol plus 400µg folic acid)

Clinical trial: 25 women with PCOS of childbearing age with oligo- or amenorrhea were took myo-inositol 2g twice a day for 6 months.

22 of 25 patients (88%) restored at least one spontaneous menstrual cycle during treatment, 18 (72%) of whom maintained normal ovulatory activity during the follow-up period. A total of 10 singleton pregnancies (40% of patients) were obtained. Nine clinical pregnancies were assessed with fetal heartbeat on ultrasound. Two pregnancies progressed to spontaneous abortion.

A prospective, controlled, randomized trial: 84 patients with PCOS: 43 participants received 2 g of MyoInositol twice daily and 41 patients received 0.6 g of D-chiro inositol twice a day. The results of our study showed that the total number of oocytes retrieved did not differ in the two treatment groups. However, the number of mature oocytes was significantly higher in the myo-inositol group compared to D-chiro-inositol. At the same time, the number of immature oocytes decreased in patients treated with myo-inositol. Furthermore, the myo-inositol treated group showed an increase in the average number of higher quality embryos and the total number of pregnancies compared to the D-chiro-inositol treated group.

Inositol acts as a secondary messenger substance within cells, but it is also an essential component of the cell membrane. Thus, Inositol is significantly involved in the optimal functioning of our body cells.

The highest concentration of Inositol, however, is found in the brain, where it carries signals and acts as a secondary messenger substance absolutely necessary for functioning essential neurotransmitters, such as serotonin, dopamine and a host of hormones. A multitude of hormones and neurotransmitters need Inositol, since it is a kind of "supporting messenger substance", allowing them to transmit their signals correctly.

Sufficient intake of Inositol therefore improves neuronal communication and signal transmission within the central nervous system, which is of paramount importance for a whole host of bodily processes. In recent years, Inositol has been the subject of research on the effects it has on certain pathologies and psychological symptoms.

Inositol also plays an important role in metabolizing carbohydrates and fats, as well as in hormonal regulation.

BIO-ACTIVE MYO-INOSITOL

Inositol exists in nine different forms, called isomers, which are distinguished by the geometric structure of the Inositol molecule. Each of these isomers exhibits some similar effects, but their properties and functions still differ to a large extent. The main form, the most frequently present in the body, is Myo-Inositol, which is involved in many bodily metabolic processes.

Nutritional information

Dosage

500mg per vegetable capsule

As a dietary supplement, two to three capsules per day. In case of acute stress, take two capsules spread over 3 doses during the day with plenty of liquid

Vegan, no additives, gluten-free, lactose-free and GMO-free.

Please note:

Do not exceed the recommended daily intake.
Food supplements do not replace a balanced and varied diet.
Store in a cool, dry place, away from light. Keep out of reach of young children.