Vitamin D3+K2 Spray 1000UI - 125 doses
- Regular price
- 15,90 €
- Regular price
- Sale price
- 15,90 €
- Unit price
- Each spray provides 1000 IU of Vitamin D3 for optimal dosing
- Contains menaquinone-7 (MK-7), a highly absorbable form of vitamin K2 and naturally occurring vitamin D3 (cholecalciferol).
- Fast and efficient absorption
- Easy administration (intra-oral spray technology)
- Suitable for vegetarians
- Natural peppermint flavor
Free delivery for orders over 65€
What is it?
Vitamin D is a fat-soluble vitamin, meaning it is soluble in fat. It is of course found in food in fatty fish (such as sardines and salmon), egg yolk, cod liver oil and more surprisingly, certain mushrooms such as chanterelles or raw chanterelles. Dietary intake of vitamin D is said to be exogenous.
As a guide: To reach the minimum recommended daily amount of 400 IU, you must eat: 8 eggs, 200g of salmon or 15L of milk - every day!
The body itself is capable of synthesizing vitamin D3 (endogenous source) by a chemical process involving a reaction between UVB (ultra-violet B rays) from the sun and the cholesterol present on the surface of the skin. Indeed, vitamin D is produced under the action of UVB rays which protolyze cholesterol in the skin into pre-vitamin D. The latter will then undergo 2 hydroxylations to be transformed into active vitamin D
There are several forms of vitamin D, vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol). Vitamin D2 (derived from plants) is the least effective since it is not correctly stored and is difficult to transform into active vitamin D3.
Vitamin D is responsible for a number of functions in the body:
➪ Vitamin D contributes to the normal absorption and utilization of calcium and phosphorus
➪ Vitamin D contributes to the maintenance of normal bones
➪ Vitamin D contributes to normal calcemia
➪ Vitamin D contributes to the maintenance of normal muscle function
➪ Vitamin D contributes to the maintenance of normal teeth
➪ Vitamin D contributes to the normal functioning of the immune system
➪ Vitamin D plays a role in the process of cell division
Vitamin D deficiency: An unfortunately common problem
Vitamin D deficiency remains a global problem, with approximately 1 billion people worldwide experiencing inadequate levels. The National Institute for Health and Care Excellence (NICE) estimates that vitamin D deficiency in France affects 1 in 5 adults and 1 in 6 children - that's 10 million of us! The SUVIMAX-OS study also concluded that "French city dwellers very often have an insufficient dietary intake of vitamin D to compensate for the lack of sunshine".
Although the recommendations state that with only 50g of salmon per day one could meet the daily vitamin D3 requirements (estimated at 15µg/d or 600UI/d) , this intake is actually insufficient in 80% of cases. Indeed, it has been estimated that the daily requirements amount to 75 IU/kg/d, i.e. between 4000-8000 IU/d for a healthy adult (considering that endogenous synthesis is nil).
However, since most of the needs are covered by synthesis in the skin through exposure to the sun, but a very large part of the population is not sufficiently exposed, food is not enough meet daily vitamin D3 requirements. This is supported by the ESTEBAN study.
Signs of vitamin D deficiency can manifest as a weakened immune system (frequent colds. ), fatigue with a drop in muscle tone, poor bone health (osteomalacia, rickets or osteoporosis) and dental (weakened enamel) or even a bad mood and attacks of tetany and convulsions in the most severe cases.
If you regularly suffer from any of these symptoms, it could be a sign that you are lacking in vitamin D!
Factors affecting the absorption or synthesis of vitamin D3 are as follows:
➣ Insufficient sun exposure
➣ Skin pigmentation (dark skin)
➣ Sun creams over 15 SPF
➣ Skin make-up
➣ Confinement (elderly people in institutions, children. )
➣ Poor, vegan or vegetarian diets
➣ Geographical location (areas with little or no sunshine)
➣ Time of year (winter and fall seasons)
Vitamin D3+KZ Osavi® is composed solely of vitamin D3 (cholecalciferol) derived from lanolin, a fat obtained from the purification and refining of suint (fatty part absorbed on sheep's wool) from sheep raised in Australia. This source of vitamin D3 therefore also responds to vegetarian diets.
It also contains menaquinone-7 (MK-7), a highly absorbable form of vitamin K2 that works synergistically with vitamin D.
➪ Vitamin K contributes to normal blood clotting and contributes to the maintenance of normal bones.
European and French legislation prevents us from communicating more about the benefits of vitamin K. We recommend that you consult various scientific data (such as reference 1 / reference 2) via the Pubmed database.
The particularity of the sprays comes from their method of administration. Indeed here, Osavi® offers an oral form of vitamin D3. This new administration technology makes it possible to circumvent the drawbacks found in the conventional administration of food supplements. Indeed, traditional supplementation (tablets, capsules, powders . ) inevitably relies on ingestion followed by digestion and absorption of the active ingredient. Nevertheless, many molecules are poorly absorbed in the intestine due to diseases (Crohn's disease, irritable bowel. ) or quite simply by the instability or poor bioavailability of the active ingredient. Added to this are the disadvantages of taking tablets by some people who have difficulty swallowing them (children, elderly people. ) or other more intimidating routes of administration such as rectal or vaginal.
Here, Osavi® provides intraoral spray technology as a delivery route for vitamin D3. The principle is simple, vitamin D3 is sprayed into the mouth through multiple micro-droplets. These micro-droplets will then be deposited on the buccal and sublingual membranes, which are very permeable and vascularized, which allows easy access to the systemic circulation without passing through the gastrointestinal system. This absorption process is very fast and makes it possible to limit the losses of molecules that could be encountered during digestion.
To prove its effectiveness, several studies have been carried out in partnership with the Universities of Cardiff, Sheffield and Ulster. One of them, for example, showed that, in a randomized, two-period, double-crossover study, oral spray supplementation was significantly more effective in terms of absorption of vitamin D3 than conventional capsule supplementation in healthy patients suffering from malabsorption syndrome. Others have demonstrated that this method of administration is effective and can supplement people suffering from diseases causing nutrient absorption problems at the gastrointestinal level.
It's not uncommon that when you go to the doctor and talk about a potential vitamin D deficiency, he or she will prescribe a high-dose vitamin D3 ampoule to cover your needs for the year. This supplementation is completely useless in the long term!
Indeed, vitamin D (in its storage form) has a half-life of 3 weeks. Thus, even if the dose taken is high, vitamin D will only be available to the body for 3 weeks. After this time, the lack will reappear. It is therefore preferable to take daily supplementation in lower doses.
Dosage: 1 spray delivers 1000 IU of vitamin D
Vitamin K2 (menaquinone-7) 15 µg
Use 1 spray daily (or as directed by your healthcare practitioner).
Can be taken at any time of the day and combined with our other oral sprays.
Press the pump 3 times to release the liquid.
Shake well before each use. Gently spray into your mouth, ideally inside your cheek, and hold for a few seconds.
Store at room temperature and out of direct sunlight. Once opened, use within 6 months.
Warnings: Do not exceed recommended dose - excessive consumption may produce laxative effects.
Food supplements should not replace a varied diet and a healthy lifestyle. Keep out of the reach and sight of children.
The opinion of our professionals
Advice of the nutrition expert
"Vitamin D is one of the most essential vitamins throughout our lives. It is essential during the growth of the child until the good aging in the elderly. Vitamin D deficiency has always existed, particularly in northern countries where the amount of sunshine is much lower than in other regions. However, today, everyone is concerned by this risk of deficiency because of our sedentary lifestyles which push us to be locked up and to protect ourselves from the sun with sunscreens or even not to eat enough or correctly. This is why it is very common to have to supplement DAILY with vitamin D3 to meet your daily needs. The route of administration in the form of an oral spray is particularly advantageous for its speed of absorption in the oral mucous membranes which are just as permeable as those of the intestinal wall but with fewer risks associated with digestion. In addition, it is a form that is suitable for everyone since here, there is no question of tablets or capsules that are difficult to swallow for a certain number of us. "
Opinion from sports coaches
"Vitamin D has two forms, vitamin D2 and vitamin D3. Vitamin D2 corresponds to the plant form (little active) while vitamin D3 (active form) comes from two different sources such as food (animal fat / food supplements) or sun exposure. When you are exposed to the sun, cholesterol reacts through a photosynthetic process which then forms cholecalciferol (inactive form of vitamin D). The cholecalciferol is then brought into the liver where it will undergo a transformation which will give rise to a compound calcifediol. In a second step, the calcifediol is transported to the kidneys where it will be transformed into calcitriol (active form of vitamin D).
The most well-known role of vitamin D is that it increases the absorption of calcium, maintaining the balance with phosphorus in our bones. It was recently discovered that vitamin D interacts with magnesium and vitamin K2. It is also known to be beneficial for our immune system. Lack of vitamin D is one of the major health deficiencies in the world. A vitamin D deficiency has serious consequences (deficient immune system, bone problems, reduced thyroid function, increased risk of cancer. )
This is why regular intake of vitamin D is recommended during periods when the sun is not very present. It is also recommended to take vitamin D for people who are exposed to little sunlight. "
"Vitamin D is essential to support your immunity even more in winter (this is the time).
It prevents cancer, autoimmune diseases, maintains strength and muscle mass, reduces insulin resistance, .
The list is long!"
Vincent Dutilly's opinion @vincent. dutilly
Without a doubt one of my favorite supplements. We keep repeating it, but vitamin D3 is essential for the proper functioning of our body as well as to strengthen our immune system. I think it would be wise to take it daily and year-round, especially during this period of Covid-19. I will advise a suitable dosage according to your body weight. (2 spray for women and 3 for men every morning)
Vitamine D3+K2 Spray 1000UI - 125 doses