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Vitamin B12 is a water-soluble vitamin essential to the body. Among other things, it contributes to the normal functioning of the nervous system and the immune system. It also contributes to normal psychological functions, to reduce fatigue, normal homocysteine metabolism and normal red blood cell formation .
Vitamin B12 is mainly found in animal products, in fact, supplementation may be necessary in the event of a vegetarian or vegan diet in order to meet daily needs.
A B-complex vitamin, vitamin B12, or cobalamin, is a red crystalline compound, earning it the nickname "vitamin red". The name cobalamin refers to its cobalt content, unique among vitamins.
Physiological role: Cobalamin is essential for growth, cell division, the proper functioning of all cells in the body and the balance of the system nervous. It intervenes more precisely in the synthesis of DNA and RNA, proteins, myelin (substance which forms a sheath around certain nerve fibers), in the formation of red blood cells, as well as in the metabolism of carbohydrates and lipids.
In food, vitamin B12 is mainly found in animal products, including organ meats and shellfish. Some products of plant origin contain it, such as miso or spirulina, but it is not certain that their form can be absorbed by the body.
A vitamin B12 deficiency causes fatigue, weakness, shortness of breath, nausea, constipation, flatulence, loss of appetite and loss of weight. It can also cause neurological symptoms: tingling and numbness in the limbs, difficulty walking, mood disorders, memory loss and dementia.
VITAMIN B12 PLATINUM is a food supplement of highly dosed and perfectly absorbable vitamin B12 in synergy with the best absorbable form of folic acid.
With VITAMIN B12 PLATINUM from Mannavital, there is now a sublingual tablet (preferably melted under the tongue) with no less than 1000 µg of the highly absorbable and effective form of vitamin B12: methylcobalamin.
Since vitamin B12 acts in many areas in synergy with folic acid, VITAMIN B12 PLATINUM also contains folic acid, and this, once again, in the best absorbable form (salt of 5-methyltetrahydrofolate glucosamine) of the reference brand Quatrefolic®.
Both vitamins are obtained by fermentation. It is also worth pointing out that this tablet is sugar-free (but with the natural sugar alcohols erythritol and xylitol) and contains natural flavor and natural coloring.
VITAMIN B12 deficiency caused by a vegan or vegetarian diet: It may take several years for a serious vitamin B12 deficiency to appear due to such a lifestyle (because that vegetarians ingest a lot of folic acid, which performs many parallel functions), but sometimes there can already be serious neurological symptoms.
In particular, if strict vegans and vegetarians do not produce enough vitamin B12 from their intestinal flora (which is generally the case), do not supplement with vitamin B12, or have a weak function of stomach (see below), then a vitamin B12 deficiency is almost inevitable.
With two tablets, it is generally sufficient, thanks to its high dosage and its form (sublingual tablet) to fill a gap (possibly at 2 tablets/day)
VITAMIN B12 deficiency due to weak stomach function, gastric diseases, after stomach surgery and “stomach reduction”: For optimal absorption in the intestine, vitamin B12 is normally bound in the stomach to "intrinsic factor". However, in case of gastric diseases or after stomach operations, this mechanism is strongly deficient, or even absent.
VITAMIN B12 Mannavital is usually sufficient to fill a vitamin B12 deficiency in these cases. Thanks to the high dosage of 1000 mcg of vitamin B12 per tablet, enough vitamin B12 can be absorbed by "passive diffusion" through the oral mucosa or further into the intestine.
PERNICIOUS ANEMIA or ANEMIA CAUSED BY VITAMIN B12 DEFICIENCY and MEGALOBLASTIC ANEMIA CAUSED BY FOLIC ACID DEFICIENCY: Possibly caused by the aforementioned vegan lifestyle or due to disorders gastric infections, "pernicious anemia" can occur due to vitamin B12 deficiency, as vitamin B12 is (along with folic acid) essential for proper cell division of red blood cell stem cells.
VITAMIN B12 Mannavital is an ideal food supplement to prevent or deal with pernicious anemia. Also in case of megaloblastic anemia due to folic acid deficiency, VITAMIN B12 (preferably 2 tablets/day) can be used: the easily absorbable and directly active form of folic acid (glucosamine salt of 5 methyltetrahydrofolate) will initially perform the main effect, but the synergy with vitamin B12 for optimal production of red blood cells is certainly welcome.
Dosage: Use: 1 to 2 tablets/day, preferably melted under the tongue.
Warnings: This product helps cover the daily vitamin B12 requirements for an adult with no absorption deficit.
Cannot replace a varied and balanced diet and a healthy lifestyle.
Contains polyols (xylitol) which can be problematic on a low FODMAP diet, especially for people with irritable bowel syndrome.
Do not exceed the recommended daily dose.
Keep out of the reach of young children.
Keep away from heat and humidity
Contraindicated in case of Leber's disease or allergy to vitamin B12.
For pregnant or breastfeeding women, or in the event of a malignant tumor, seek advice from a healthcare professional before any supplementation.
Drug Interactions:
Reduction of gastric acidity by these drugs which can reduce the digestive absorption of vitamin B12.
-Selon l’EFSA, la vitamine B12 :
Des études ont montré l’intérêt de la vitamine B12 dans :
| Ingrédients actifs | Par comprimé | % VNR* |
|---|---|---|
| Vitamine B12 (Méthylcobalamine) | 1000 µg | 40 000 % |
| Acide folique (Quatrefolic® - 5-MTHF) | 200 µg | 100 % |
*VNR = Valeurs Nutritionnelles de Référence
Ingrédients : édulcorants naturels (xylitol, érythritol), méthylcobalamine (vitamine B12), 5-méthyltétrahydrofolate sous forme de sel de glucosamine (Quatrefolic®), arôme naturel (cerise), colorant naturel (jus de betterave rouge).
Origine : Ingrédients obtenus par fermentation.
Sans sucre ajouté. Convient aux végétariens et végétaliens. Sans gluten. Sans lactose.
Utilisation conseillée : 1 à 2 comprimés par jour, à laisser fondre de préférence sous la langue.
Précautions d’emploi :
Conservation : À conserver à l’abri de la chaleur, de l’humidité et de la lumière.
-La vitamine B12, ou méthylcobalamine dans sa forme active, est essentielle au bon fonctionnement de l’organisme. Elle joue un rôle clé dans la division cellulaire, la synthèse de l’ADN, la formation des globules rouges et le maintien du système nerveux.
En synergie avec l’acide folique (Quatrefolic®), elle participe à la prévention de l’anémie mégaloblastique et à la régulation du métabolisme de l’homocystéine, un facteur de risque cardiovasculaire.
La prise sublinguale permet de contourner les déficits d’absorption gastro-intestinaux (manque de facteur intrinsèque, gastrectomie, etc.) et assure une biodisponibilité optimale.
La méthylcobalamine est la forme active directement utilisable par l’organisme, contrairement à la cyanocobalamine qui nécessite une transformation préalable dans le foie.
Besoins journaliers recommandés :
Un apport de 1000 µg permet de corriger efficacement les carences et de compenser une absorption digestive réduite.
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